SUBMIT MANUSCRIPT

Pyrex Journal of Biomedical Research (PJBR)

February 2017 Vol. 3 (2), pp. 7-11

ISSN: 2579-1222

Copyright 2017 Pyrex Journals




Full Length Research Paper


Serum Magnesium and Copper levels were associated with Ambulation in Type 2 Diabetic Patients


Abo-Baker Mohammed Al-Amin1, Khalid Gindeel Abu-Baker2 and AbdElkarim A. Abdrabo1*

1Department of Chemistry, Faculty of Medical laboratory Sciences, Al-Neelain University, Sudan.

2Elrhyada Medical Complex, Clinical Laboratory Service, Portsudan, Sudan.

Corresponding Author E-mail: abdrabokarim@hotmail.com

Accepted 17th February, 2017



Abstract


Background: A relationship between diabetes mellitus (DM) and minerals is frequently reported, Alteration in the metabolism of trace elements like copper, magnesium is associated with DM. Alteration in mineral metabolism is more pronounced in diabetic populations with specific complications. Objectives: to estimate levels of magnesium and copper in serum of type 2 DM patients with amputation. Materials and methods: the study included eighty (80) subjects, (40) of them are with DM type 2 with complication, amputation (20), and (40) represent DM type 2 without complication groups. Magnesium, copper and HbA1c were estimated in the blood of all participants. Results: The mean concentration of copper was significantly increased among diabetic patient type 2 with complication compared to diabetic patient without complication p-value 0.012. The mean concentration of magnesium was significantly decreased among diabetic patient complication compared to a patient without complication p-value 0.011. Conclusion: Lower levels of magnesium and higher levels of copper were significantly associated with complications in type 2 diabetes mellitus.

Keywords: Type 2 DM, Magnesium, Copper, HbA1c, Amputation.

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