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Pyrex Journal of Biomedical Research (PJBR)

December 2016 Vol. 2(6), pp. 48-51

ISSN: 2985-8852

Copyright 2016 Pyrex Journals




Full Length Research Paper


Effect of Hemodialysis on Serium Uric Acid, Urea, Creatinine and Albumin Level in Chronic Renal Failure Patients


Mozdalifa Mohy Eldeen Mohamed Ahmed1* and Omar Fadul Idres2

1Department of Clinical Chemistry, Faculty of Medical Laboratory Science, University of AL-Neelain, Sudan.
2Department of Medical Genetics, Faculty of Medicine, Cumhuriyet University 58140, Sivas-Turkey.

Corresponding Author E-mail: emad198780@hotmail.com

Accepted 17th November, 2016



Abstract


The aim of this study was to assess the effect of hemodialysis on serum uric acid, urea, creatinine and albumin level among CRF patients. A cross-sectional study included 50 subjects 20 female and 30 male attended to regular dialysis in police teaching hospital aged (25-80 years old) were included, timed pre and post-hemodialysis samples were collected. Serum uric acid, urea, creatinine and albumin were measured by using Mindray Bs-200, and BMI was estimated. Paired t-test analyses showed significant decrease in the mean of uric acid, urea and creatinine levels in post dialysis samples with p-value (0.00, 0.000 and 0.000) when compared to pre dialysis samples, while showed significant increase of albumin level in post dialysis samples with p-value (0.000). Person's correlation showed positive correlation between BMI and creatinine level, and no correlation noted between change in serum albumin level and reduction in urea and creatinine. The Study concludes that, hemodialysis increase serum albumin and decrease serum uric acid, urea and creatinine level.

Keywords: Uric acid, urea, creatinine, albumin CRF, dialysis and hemodialysis.

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