Pyrex Journal of Biomedical Research (PJBR)

November 2015 Vol. 1(5), pp. 045-054

Copyright 2015 Pyrex Journals




Original Research Article


The Split-Function Effect of Renal Scintigraphy for the Evaluation of Renal Disorders Due to Tc- DTPA Pharmaceutical


Alamgir Hossain1* and Samiron Kumar Saha2

1Department of Physics, University of Rajshahi, Bangladesh.
2Department of Physics, Pabna University of Science & Technology, Bangladesh.

Corresponding Author E-mail: alamgir_ru07@yahoo.com

Accepted 12th November, 2015



Abstract


Purpose: The purpose of this study was to clarify renal disorders on the split-function effect of renal scintigraphy due to Tc- DTPA pharmaceutical. Methods: The experiments were carried out in the Centre for Nuclear Medicine and Ultrasound, Rajshahi. 18patients were taken under our study. The patients were given 5 mCi intravenously 99mTc injections. The exam was performed using a gamma camera equipped with a low energy and high resolution collimator. On the day of the exam, the patients drank 600 ml of water before radioisotope injection. The bladder was emptied immediately before the exam and the patients were then positioned with the gamma camera in contact with their back. Sequential images were acquired and fed to the computer for 20 min. Results: In this research, Split function, increased with patient age (Normal), kidney depth, Time of Max, Kidney Counts (Abnormal) and patient height. On the other hand, Split- function, decreased with patient age (normal), Time of Max, Kidney Counts (Normal) and patient weight. Therefore, split-function does influence great role for diagnosis various renal disorders. Conclusion: 99mTc DTPA can evaluate renal disorders with more findings and provided that split function can measure an early investigation for clinical diagnosis of renal disorders.

Keywords: Renal disorder, 99mTc-DTPA, Renal differential function, Kinetic behavior.

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